top of page
Search
  • Mansfeld Lab

Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.


Alena's first paper from a beautiful collaboration with Anna Liess from Sonja Lorenz' group in Würzburg just got published in Structure! Combining structural biology, biochemistry and cell biology our labs together reveal how ubiquitination of a conserved lysine residue close to the active site of the E2 ubiquitin-conjugating enzyme UBE2S regulates its activity and thereby the ability to generate K11-linked ubiquitin chains during mitosis.

Have a look here to read the full story and below to see a happy Alena - Well deserved!!

67 views0 comments

Recent Posts

See All
bottom of page