Publications and pre-prints

UFMylation regulates translational homeostasis and cell cycle progression

 

Igor A. Gak*, Djordje Vasiljevic*, Thomas Zerjatke, Lu Yu, Mario Brosch, Theodoros I. Roumeliotis, Cindy Horenburg, Nancy Klemm, Gábor Bakos, Alexander Herrmann, Jochen Hampe, Ingmar Glauche, Jyoti S. Choudhary and Jörg Mansfeld.

BioRxiv, doi: 10.1101/2020.02.03.931196                                                                         

*shared first authorship

Redox potential defines functional states of adult hippocampal stem cells.

 

Vijay S Adusumilli, Tara L Walker, Rupert W Overall, Gesa M Klatt, Salma A Zeidan, Tim J Fischer, Sara Zocher, Alex M Sykes, Susanne Reinhardt, Andreas Dahl, Dilyana G Kirova, Jörg Mansfeld, Annette E Rünker, Gerd Kempermann (2019).

Cell Stem Cell 2021 Feb 4;28(2):300-314.e6. doi: 10.1016/j.stem.2020.10.019.

Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.

 

Anna K. L. Liess*, Alena Kucerova*, Kristian Schweimer, Dörte Schlesinger, Olexandr Dybkov, Henning Urlaub, Jörg Mansfeld# and Sonja Lorenz# (2020).

Science Signaling (13), 654:eaba8208. doi: 10.1126/scisignal.aba8208

                                                                                                                                          *shared first authorship

                                                                                                                                          #corresponding authors

Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures.

 

Katharina B Beer, Gholamreza Fazeli, Kristyna Judasova, Linda Irmisch, Jona Causemann, Jörg Mansfeld, Ann M Wehman (2019).

Nature Communications 10:3490. doi: 10.1038/s41467-019-11442-z

Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.

 

Anna K.L. Liess*, Alena Kucerova*, Kristian Schweimer, Lu Yu, Theodoros I. Roumeliotis, Mathias Diebold, Olexandr Dybkov, Christoph Sotriffer, Henning Urlaub, Jyoti S. Choudhary, Jörg Mansfeld#, Sonja Lorenz#

(2019).

Structure. 2019 Jun 20,  doi: 10.1016/j.str.2019.05.008

                                                                                                                                          *shared first authorship

                                                                                                                                          #corresponding authors

An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules.

 

Bakos, G., Yu l., Gak IA., Roumeliotis, TI., Liakopoulos D., Choudhary JS. and Mansfeld J. (2018).

Nature Communications 9:4776. doi: 10.1038/s41467-018-07251-5

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody.

 

Daniel K*., Icha, J*.,  Horenburg, C., Müller D., Norden C#., and Mansfeld J#. (2018).

Nature Communications 9:3297. doi: 10.1038/s41467-018-05855-5

*shared first authorship

                                                                                                                                          #corresponding authors

PLK1 Activation in Late G2 Sets Up Commitment to Mitosis.

 

Gheghiani L.,  Loew D., Lombard B., Mansfeld J., and  Gavet O. (2017).

Cell Reports 19:2060-73. doi: 10.1016/j.celrep.2017.05.031

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

 

Hein, MY., Hubner NC., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak I., Weisswange i., Mansfeld J., Buchholz F., Hyman AA., Mann M. (2015).

Cell 163(3):712-23. doi: 10.1016/j.cell.2015.09.053

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping.

 

Otto, O., Rosendahl, P., Mietke, A., Golfier, S., Herold, C., Klaue, D., Girardo, S., Pagliara, S., Ekpenyong, A., Jacobi, A.,Wobus M., Toepfer N., Keyser UF., Mansfeld J., Fischer-Friedrich E., Guck, J. (2015).

Nature Methods 12(3):199-202. doi:10.1038/nmeth.3281

The ABBA Motif Binds APC/C Activators and Is Shared by APC/C Substrates and Regulators.

 

Di Fiore, B., Davey, N. E., Hagting, A., Izawa, D., Mansfeld, J., Gibson, T. J., and Pines, J. (2015).

Developmental Cell 32:358–372. doi: 10.1016/j.devcel.2015.01.003

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

 

Mansfeld, J., Collin, P., Collins, M. O., Choudhary, J. S., and Pines, J. (2011).

Nature Cell Biology 13:1234–1243. doi: 10.1038/ncb2347

Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.

 

Mitchell, J. M., Mansfeld, J., Capitanio, J., Kutay, U., and Wozniak, R. W. (2010).

Journal of J Cell Biology 191:505–521. doi: 10.1083/jcb.201007098

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

 

Garnett, M. J*., Mansfeld, J*., Godwin, C., Matsusaka, T., Wu, J., Russell, P., Pines, J., and Venkitaraman, A. R. (2009).

Nature Cell Biology 11:1363–1369. doi: 10.1038/ncb1983                                                                             

*shared first authorship

The actin multigene family of Paramecium tetraurelia.

 

Sehring, I. M., Mansfeld, J., Reiner, C., Wagner, E., Plattner, H., and Kissmehl, R. (2007).

BMC Genomics 8:82. doi: 10.1186/1471-2164-8-82

A broad spectrum of actin paralogs in Paramecium tetraurelia cells display differential localization and function.

 

Sehring, I. M., Reiner, C., Mansfeld, J., Plattner, H., and Kissmehl, R. (2007).

Journal of Cell Science 120: 177–190. doi: 10.1242/jcs.03313

The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.

 

Mansfeld, J*., Güttinger, *S., Hawryluk-Gara, L. A., Panté, N., Mall, M., Galy, V., Haselmann, U., Mühlhäusser, P., Wozniak, R. W., Mattaj, I. W., Kutay U#. and Antonin W#. (2006).

Molecular Cell 22:93–103. doi: 10.1016/j.molcel.2006.02.015                                                                                       

*shared first authorship

 #corresponding authors

A multigene family encoding R-SNAREs in the ciliate Paramecium tetraurelia.

 

Schilde, C., Wassmer, T., Mansfeld, J., Plattner, H., and Kissmehl, R. (2006).

Traffic 7:440–455. doi: 10.1111/j.1600-0854.2006.00397.x