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  • Mansfeld Lab

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody


Finally, after three rounds of revisions Katrin's paper on an auxin-dependent nanobody to target GFP-tagged proteins for degradation has been published in Nature Communications. If you ever wanted to get rid of your favorite GFP-tagged protein try our mAID-nanobody! Together with Jaroslav Icha from Caren Norden's lab and help from Cindy and Doris we show that mAID-nanobody-dependent degradation works in human cell lines and in zebrafish. Thereby, we demonstrate for the first time that the auxin system can also be applied to a vertebrate model organism. Have a look here to find out how it works!

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